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Stephen Heller


Specialty: Organic Chemistry

Headshot of Stephen Heller

Contact Information

Salem Campus

Address
Olin Science Center 316
900 State Street
Salem  Oregon  97301
U.S.A.
Phone
503-370-6371

Biography

Education

  • Ph.D., University of California, Berkeley
  • B.S., University of Chicago

Professional Interests

Development of new methodologies for the synthesis of pharmaceutically relevant heterocycles; design and study of novel chemoselective acylating reagents; total synthesis of bioactive natural products.

Personal Interests

Steve enjoys hiking, ultimate frisbee, coffee, all types of dogs, and wonking out on educational policy.

Publications

  • Heller, S.T.; Schultz, E.E.; Sarpong, R. Chemoselective N-Acylation of Indoles and Oxazolidinones withCarbonylazoles. Angewandte Chemie International Edition, 2012, 51, 8304.
  • Heller, S.T.; Fu, T.; Sarpong, R. Dual Brønsted Acid/Nucleophilic Activation of CarbonylimidazoleDerivatives. Organic Letters, 2012, 14, 1970.
  • Heller, S.T.; Sarpong, R. On the Reactivity of Imidazole Carbamates and Ureas and their Use as Esterification and Amidation Reagents. Tetrahedron, 2011, 67, 8851.
  • Heller, S.T.; Sarpong, R. Chemoselective Esterification and Amidation of Carboxylic Acids with ImidazoleCarbamates and Ureas. Organic Letters, 2010, 12, 4572.
  • Heller, S.T.; Ross, R.; Irvine, N.M.; Renga, J.M.; Zettler, M.W.; Arndt. Process for the Preparation of 2-Substituted-5-(1-Alkylthio)alkylpyridines. K.E. PCT Int. Appl. 2008, WO 2008066558.
  • Heller, S.T.; Natarajan, S.R. Rapid Access to Pyrazolo[3,4-c]pyridines via Alkyne Annulation: Limitations of Steric Control in Nickel-Catalyzed Alkyne Insertions. Organic Letters, 2007, 9, 4947.
  • Natarajan, S.R.; Heller, S.T.; Nam, K.; Singh, S.B.; Scapin, G.; Patel, S.; Thompson, J.E.; Fitzgerald, C.E.; O’Keefe, S.J. p38 MAP kinase inhibitors. Part 6: 2-Arylpyridazin-3-ones as templates for inhibitor design. Bioorganic and Medicinal Chemistry Letters, 2006, 16, 5809.
  • Natarajan, S.R.; Chen, M.-H.; Heller, S.T.; Tynebor, R.M.; Crawford, E.M. ; Minxiang, C.; Kaizheng,H.; Dong, J.; Hu, B.; Hao, W.; Chen, S.H. Synthesis of the 2H-Quinolizin-2-one Scaffold via a StepwiseAcylation—Intramolecular Annulation Strategy. Tetrahedron Letters, 2006, 47, 5063.
  • Heller, S.T.; Natarajan, S.R. 1,3-Diketones from Acid Chlorides and Ketones: A Rapid and General One-PotSynthesis of Pyrazoles. Organic Letters, 2006, 8, 2675.
  • Lee, D.-C.; Chang, B.-J.; Morales, G.M.; Jang, Y.A.; Ng, K.-K.; Heller, S.T.; Yu, L. Functional Polymers for Layer-by-Layer Construction of Multilayers via Chemoselective Immobilization. Macromolecules, 2004, 37,1849.
  • Casmier, D.M.; Sullivan, P.A.; Clot, O.; Firestone, K.; Lee, S.; Heller, S.; Brumbaugh, A.; Millard, B.; Dalton, L.R. New Paradigm in NLO Chromophore Design through a Gradient Bridge Concept. Proc. SPIE 5351, 2004, 243.
Willamette University

Department of Chemistry

Address
Willamette University
900 State Street
Salem Oregon 97301 U.S.A.
Phone
503-370-6013 voice
503-375-5425 fax